The ubiquitous and interconnected vascular system plays critical roles throughout the body. It regulates vasotone and hemostasis, propagates inflammatory responses and interacts with many other cell types. Vascular inflammation and dysfunction is a primary driving force behind the most prevalent human diseases, such as cardiovascular diseases and diabetic complications and is a critical driver of serious lung, liver and kidney diseases.
Riparian is leveraging the fascinating observation that select regions of blood vessels, shared between humans and across species, are naturally protected from inflammation and vascular dysfunction. Riparian’s first-in-class therapeutic program focuses on exploiting this protective biology.
We are scientists. We are driven to discover and unlock the potential of new biology. Beyond the biology, we are also inspired to make impactful contributions to vascular health, an essential and underserved part of human health.
JLABS provided the resources and network to acquire early key data critical for our program’s advancement and fundraising.