Residents

Stemiotics Inc.

Stemiotics Inc.

At Stemiotics, Inc we generate iPSCs from human fibroblasts by using messenger RNA (mRNA) transfection, the fastest and most efficient method yet devised for reprogramming these cells to pluripotency. Since mRNA is rapidly degraded inside cells our reprogramming system is completely “footprint-free.” The mRNA system also eliminates any need to purge or screen for residual traces of vector, as entailed by other popular non-integrating strategies relying on episomal DNA or Sendai virus. We use only xeno-free reagents at all steps in our pipeline, from fibroblast recovery to reprogramming to stem cell expansion to iPSC freeze-down. We do not use feeder cells, conditioned media or small molecules (with their potential for off-target effects) at any stage in the iPSC production process.

Area of focus: 
Platform / research tool
Graduation date: 
03/11/2016
Commencement date: 
01/15/2014

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